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Minnesota hopes to bounce back from a shocking loss to Bowling Green when it hosts Purdue on Saturday afternoon. The Golden Gophers, who were 30.5-point favorites at Caesars Sportsbook, are now 2-2 on the season. Purdue is coming off a 13-9 win over Illinois, failing to cover as a 10.5-point favorite. The Boilermakers have lost seven of their last eight games against Minnesota.

Kickoff is set for noon ET. The Boilermakers are 2.5-point favorites in the latest Purdue vs. Minnesota odds at Caesars Sportsbook, while the over-under for points scored is 46.5. Before entering any Minnesota vs. Purdue picks, you'll want to see the college football predictions from the model at SportsLine.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. After going a sizzling 9-3 in Week 4, It also enters Week 5 of the 2021 season on an 81-61 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Purdue vs. Minnesota. You can head to SportsLine to see its picks. Here are several college football odds for Minnesota vs. Purdue:

  • Purdue vs. Minnesota spread: Purdue -2.5
  • Purdue vs. Minnesota over-under: 46.5 points

What you need to know about Purdue

Even if it wasn't a dominant performance, the Boilermakers beat the Illinois Fighting Illini 13-9 last Saturday. Purdue had just 42 yards on the ground but QBs Jack Plummer and Aidan O'Connell combined for 277 yards through the air. Plummer started the game but it was O'Connell who came in and engineered the game-winning drive and touchdown pass to TJ Sheffield.

Meanwhile, the Boilermakers' defense has been stout all year and currently ranks ninth nationally in scoring defense. Purdue has allowed just six total touchdowns through four games and only 176.8 yards through the air. Leading the defensive effort is DE George Karlaftis, who is tied for the team lead in sacks (1.5) and leads the Big Ten with two forced fumbles.

What you need to know about Minnesota

Purdue was without its top two running backs against Illinois last week and it could be missing them again on Saturday. Head coach Jeff Brohm chose to play two quarterbacks and they were only able to score 13 points. The Boilermakers totaled just 38 rushing yards, so Minnesota will try to make them one-dimensional in this game.

The Golden Gophers are coming off an embarrassing loss and should be motivated on Saturday. They are led by running back Trey Potts, who carried the ball 27 times for 141 yards against Bowling Green. Defensive lineman Boye Mafe is tied for second in the Big Ten with four sacks-he can make life difficult for Purdue's offensive line. 

How to make Minnesota vs. Purdue picks

The model has simulated Purdue vs. Minnesota 10,000 times and the results are in. The model is leaning over on the total, and it also says one side of the spread hits in more than 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Minnesota vs. Purdue? And which side of the spread hits more than 50 percent of the time? Visit SportsLine now to see which side of the Purdue vs. Minnesota spread to back, all from the advanced model that is up almost $3,300 on its top-rated college football spread picks, and find out.